Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100697968zf-4CXXC_R1 domain-containing protein. (403 aa)    
Predicted Functional Partners:
ENSONIP00000038349
RING finger protein 223.
   
 0.480
I3J608_ORENI
NBR1 autophagy cargo receptor b.
   
 0.476
nbr1
NBR1 autophagy cargo receptor a.
   
 0.476
tradd
Tnfrsf1a-associated via death domain.
    
 0.472
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.470
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.470
mib2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.457
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
  0.453
gak
Cyclin G associated kinase.
    
 0.431
I3KP91_ORENI
Mitogen-activated protein kinase kinase 7.
   
 0.427
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (12%) [HD]