Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
LOC102082909Si:ch211-114c12.2. (627 aa)    
Predicted Functional Partners:
dld
Dihydrolipoyl dehydrogenase.
   
 0.963
pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.960
pdhx
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 0.921
dlat
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.921
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
   
 0.899
mdh2
Malate dehydrogenase.
  
 0.750
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.747
cdca8
Cell division cycle associated 8.
  
 0.703
LOC100693141
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.703
LOC100692119
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.684
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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