Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3JCA9_ORENICysteine and histidine-rich domain (CHORD) containing 1a. (331 aa)    
Predicted Functional Partners:
sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
   
 0.890
ppp5c
Serine/threonine-protein phosphatase.
   
 0.859
Hsp90ab1
Heat shock protein 90, alpha (cytosolic), class B member 1.
   
 0.797
LOC100701982
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.
   
 0.797
ttc4
Tetratricopeptide repeat domain 4.
    
   0.765
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.763
edrf1
Erythroid differentiation regulatory factor 1.
    
   0.720
ENSONIP00000000885
TSC complex subunit 1a.
   
 0.633
trap1
TNF receptor-associated protein 1.
   
 0.633
LOC100704495
TSC complex subunit 1b.
   
 0.633
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (8%) [HD]