Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1384 aa)    
Predicted Functional Partners:
pde3b
Phosphodiesterase.
   
 0.958
LOC100709658
Uncharacterized protein.
    
 0.950
LOC100710082
GNAS complex locus.
    
 0.950
GNAS
Guanine nucleotide-binding protein G(s) subunit alpha isoform X1.
    
 0.950
LOC100699977
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
 0.939
LOC100702054
Guanine nucleotide binding protein (G protein), beta 5b.
    
 0.938
LOC100703527
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
    
 0.936
I3J8H8_ORENI
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
    
 0.936
LOC100695013
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.
    
 0.936
gng10-2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.934
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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