Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100704978Coronin; Belongs to the WD repeat coronin family. (930 aa)    
Predicted Functional Partners:
klhl20
Kelch-like family member 20.
    
 
 0.873
ACTR3B
Actin related protein 3C; Belongs to the actin family.
    
 
 0.617
LOC100699229
Uncharacterized protein; Belongs to the actin family.
    
 
 0.617
LOC100711948
Actin related protein 3; Belongs to the actin family.
    
 
 0.617
kbtbd8
Kelch repeat and BTB (POZ) domain containing 8.
    
 
 0.565
KLHL28
Kelch like family member 28.
    
 
 0.554
arpc5
Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
    
 
 0.526
I3IZQ5_ORENI
Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
    
 
 0.526
Rnf166
RING finger protein 166 isoform X1.
      
 0.496
ENSONIP00000035480
Actin related protein 2/3 complex, subunit 4.
    
 
 0.492
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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