Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
samsn1SAM domain, SH3 domain and nuclear localisation signals 1a. (468 aa)    
Predicted Functional Partners:
def8
Differentially expressed in FDCP 8 homolog.
   
  
 0.724
LOC100712466
Uncharacterized protein.
   
  
 0.647
cnih4
Cornichon family AMPA receptor auxiliary protein 4.
      
 0.616
mettl9
Methyltransferase like 9.
      
 0.595
spg21
SPG21 abhydrolase domain containing, maspardin.
      
 0.577
dffb
DNA fragmentation factor, beta polypeptide (caspase-activated DNase).
      
 0.528
I3J919_ORENI
Serotransferrin; Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.
      
 0.501
meltf
Serotransferrin; Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.
      
 0.501
LOC100691316
Serotransferrin-like.
      
 0.501
tmem141
Transmembrane protein 141.
      
 0.479
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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