Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100705244Heme oxygenase 2b. (309 aa)    
Predicted Functional Partners:
blvrb
Biliverdin reductase B.
    
 0.938
blvra
Biliverdin reductase A.
     
 0.923
fech
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
    
 0.918
Fxn
Frataxin, mitochondrial.
     
 0.898
LOC100704391
Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
    
 0.885
LOC100702360
Hephaestin-like 1b; Belongs to the multicopper oxidase family.
     
 0.879
LOC100702684
Ceruloplasmin; Belongs to the multicopper oxidase family.
     
 0.879
LOC100695060
Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.
     
 0.872
LOC100692842
Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
     
 0.869
LOC100701438
Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
  
 
 0.807
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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