STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccnfCyclin F; Belongs to the cyclin family. (786 aa)    
Predicted Functional Partners:
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.965
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.949
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
   
 0.899
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.866
espl1
Extra spindle pole bodies like 1, separase.
   
  
 0.842
cdc20
Cell division cycle 20 homolog.
   
 0.829
ENSONIP00000057827
Cell division cycle protein 20 homolog B isoform X1.
   
 0.829
cdt1
Chromatin licensing and DNA replication factor 1.
   
 0.806
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.779
anapc4
Anaphase promoting complex subunit 4.
    
 0.768
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.