Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100709965Midline 2. (770 aa)    
Predicted Functional Partners:
igbp1
Immunoglobulin (CD79A) binding protein 1.
    
 
 0.786
rnf41
Ring finger protein 41.
    
 0.659
ptpa
Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
    
 
 0.648
pcnp
PEST proteolytic signal containing nuclear protein.
      
 0.427
Rd3
Retinal degeneration 3, GUCY2D regulator.
      
 0.410
FSD2
Fibronectin type III and SPRY domain containing 2.
      
 0.409
LOC100710281
Serine/threonine-protein phosphatase.
    
 
 0.407
LOC100705713
Serine/threonine-protein phosphatase.
    
 
 0.407
ppp2ca
Serine/threonine-protein phosphatase.
    
 
 0.407
creb5
cAMP responsive element binding protein 5b.
    
   0.402
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.