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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3JCJ3_ORENITNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (232 aa)    
Predicted Functional Partners:
ENSONIP00000016286
annotation not available
   
 0.791
I3JR76_ORENI
Uncharacterized protein.
    
 0.726
LOC102082670
TNFR-Cys domain-containing protein.
    
 0.726
ENSONIP00000073708
Tumor necrosis factor receptor superfamily member 14.
    
 0.726
LOC109204105
Tumor necrosis factor receptor superfamily member 6B isoform X1.
    
 0.710
ENSONIP00000059106
annotation not available
    
 0.710
LOC100691514
Uncharacterized protein.
    
 0.710
I3KSQ8_ORENI
TNFR-Cys domain-containing protein.
    
 0.706
LOC102081429
TNF receptor superfamily member 11b.
    
 0.525
LOC100690570
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
     
 0.490
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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