Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100695939Fascin. (491 aa)    
Predicted Functional Partners:
I3J143_ORENI
Espin.
    
 0.606
LOC100690913
Espin like a.
    
 0.606
twf1
Twinfilin actin-binding protein 1a.
     
 0.600
grxcr1
Glutaredoxin and cysteine rich domain containing 1 a.
     
 0.546
GRXCR2
Glutaredoxin and cysteine rich domain containing 2.
     
 0.542
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
     
 0.521
LOC100710621
Myosin Ic, paralog a; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
     
 0.483
myo1c
Myosin Ic, paralog b; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
     
 0.483
LOC100697050
FERM domain-containing protein.
     
 0.470
ENSONIP00000028767
annotation not available
     
 0.468
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.