Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccdc137Coiled-coil domain containing 137. (262 aa)    
Predicted Functional Partners:
rbm34
RNA binding motif protein 34.
   
 
 0.935
nol12
Nucleolar protein 12.
   
   0.916
gpatch4
G patch domain containing 4.
   
   0.773
rrp8
Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.
    
   0.771
ccdc25
Coiled-coil domain containing 25.
      
 0.723
rpf2
Ribosome production factor 2 homolog.
    
 
 0.717
mrpl12
39S ribosomal protein L12, mitochondrial.
      
 0.665
Rpl37a
Large subunit ribosomal protein L37Ae.
    
   0.657
gtpbp4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
      
 0.651
znf622
Zinc finger protein 622.
      
 0.634
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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