Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
LOC100693968Activating transcription factor 5a. (505 aa)    
Predicted Functional Partners:
cebpg
CCAAT enhancer binding protein gamma.
   
 0.915
LOC100700105
Tribbles pseudokinase 3.
   
 0.828
eif2s1
Eukaryotic translation initiation factor 2, subunit 1 alpha b.
    
 0.722
LONP1
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.
     
 0.648
ddit3
Uncharacterized protein.
  
 0.643
clpp
ATP-dependent Clp protease proteolytic subunit.
      
 0.625
vps53
VPS53 subunit of GARP complex.
      
 0.618
asns
Asparagine synthetase [glutamine-hydrolyzing].
   
 0.604
pnkp
Polynucleotide kinase 3'-phosphatase.
      
 0.600
LOC100704429
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
   
 
 0.558
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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