Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cfl1Cofilin 1; Belongs to the actin-binding proteins ADF family. (150 aa)    
Predicted Functional Partners:
limk2
LIM domain kinase 2.
   
 0.993
LOC100693040
LIM domain kinase 1a.
   
 0.988
LOC100704692
LIM domain kinase 1b.
   
 0.977
ssh1
Slingshot protein phosphatase 1a.
    
 0.967
LOC100694270
Slingshot protein phosphatase 1b.
    
 0.967
ENSONIP00000056756
Si:ch211-203d1.3.
    
 0.967
Ssh2
Slingshot protein phosphatase 2a.
    
 0.948
LOC100702311
Slingshot protein phosphatase 2b.
    
 0.948
LOC100704245
Uncharacterized protein.
   
 0.946
actb
Uncharacterized protein.
   
 0.946
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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