Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
corinCorin, serine peptidase. (1105 aa)    
Predicted Functional Partners:
LOC100705260
Uncharacterized protein.
     
 0.904
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
      
 0.841
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
      
 0.795
IGFBP1
Insulin like growth factor binding protein 1.
    
 0.711
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.683
LOC100692694
Inositol 1,4,5-trisphosphate receptor, type 1b.
      
 0.680
I3KSK9_ORENI
Inositol 1,4,5-trisphosphate receptor, type 1a.
      
 0.680
slc45a1
Solute carrier family 45 member 1.
      
 0.677
slc45a2
Solute carrier family 45 member 2.
      
 0.677
ENSONIP00000052427
annotation not available
    
 0.667
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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