STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
get1Guided entry of tail-anchored proteins factor 1. (170 aa)    
Predicted Functional Partners:
get3
ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]
    
 0.997
Camlg
Calcium modulating ligand.
    
 0.978
Sec61b
Protein transport protein SEC61 subunit beta.
    
 0.778
get4
Guided entry of tail-anchored proteins factor 4.
    
 0.763
gart
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
      
 0.702
sec63
SEC63 homolog, protein translocation regulator.
      
 0.678
I3JK34_ORENI
Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha.
    
 0.651
sgtb
Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta.
    
 0.651
TMEM208
Transmembrane protein 208.
    
 
 0.627
emc6
ER membrane protein complex subunit 6.
    
 
 0.618
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (40%) [HD]