Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast). (202 aa)    
Predicted Functional Partners:
mad1l1
Mitotic arrest deficient 1 like 1.
    
 0.999
bub1b
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 0.999
bub3
BUB3 mitotic checkpoint protein.
   
 0.999
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.999
cdc27
Cell division cycle 27.
   
 0.998
cdc23
CDC23 (cell division cycle 23, yeast, homolog).
    
 0.998
cdc16
Cell division cycle 16 homolog (S. cerevisiae).
   
 0.998
anapc4
Anaphase promoting complex subunit 4.
    
 0.997
anapc10
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
    
 0.997
I3IXS1_ORENI
Anaphase promoting complex subunit 1.
    
 0.994
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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