Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
LOC100698564Ribosomal protein S6 kinase. (747 aa)    
Predicted Functional Partners:
tsc2
Rap-GAP domain-containing protein.
   
 0.958
atf4
Activating transcription factor 4a.
    
 0.942
LOC100704495
TSC complex subunit 1b.
    
 0.939
LOC100706109
Activating transcription factor 4b.
    
 0.935
LOC100698798
TBC1 domain family, member 7.
     
 0.928
LOC100697722
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.921
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.921
pkmyt1
Protein kinase, membrane associated tyrosine/threonine 1.
     
  0.916
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
     
  0.916
Rps6ka6
Ribosomal protein S6 kinase.
     
  0.832
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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