Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100707355Microtubule-associated protein, RP/EB family, member 3b. (359 aa)    
Predicted Functional Partners:
mphosph8
M-phase phosphoprotein 8.
   
 0.917
ckap5
Cytoskeleton associated protein 5.
   
 0.863
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.854
bub3
BUB3 mitotic checkpoint protein.
   
 0.822
mad1l1
Mitotic arrest deficient 1 like 1.
    
 0.806
LOC100695973
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
   
 0.768
LOC100699478
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family.
   
 0.768
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.757
cenpe
Centromere-associated protein E isoform X1.
   
 0.750
bub1b
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 0.748
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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