Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100692187Spartin b. (609 aa)    
Predicted Functional Partners:
I3J4H0_ORENI
IST1 factor associated with ESCRT-III.
    
 
 0.928
spart
Spartin a.
     
  0.916
LOC100697163
E3 ubiquitin-protein ligase.
    
 
 0.915
LOC100694718
E3 ubiquitin-protein ligase.
    
 
 0.915
LOC100701023
WW domain containing E3 ubiquitin protein ligase 1.
    
 
 0.808
wwp2
E3 ubiquitin-protein ligase.
    
 
 0.808
tor4a
Torsin family 4, member Aa.
      
 0.737
nipa1
NIPA magnesium transporter 1.
      
 0.726
trim45
Tripartite motif containing 45.
      
 0.702
spg21
SPG21 abhydrolase domain containing, maspardin.
      
 0.687
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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