Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100698560Sodium channel, voltage-gated, type II, beta. (218 aa)    
Predicted Functional Partners:
LOC100691202
Sodium channel, voltage-gated, type I, beta a.
   
 0.995
scn1b
Ig-like domain-containing protein.
  
 0.989
scn3b
Sodium channel, voltage-gated, type III, beta.
   
 
 0.923
LOC100711422
Sodium channel, voltage-gated, type IV, beta b.
   
 
 0.856
LOC100691739
Si:ch211-225p5.8.
  
  
  0.845
I3KEH8_ORENI
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 0.824
I3KEX6_ORENI
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 0.824
LOC100698831
Sodium channel, voltage-gated, type IV, beta a.
   
 
 0.812
cxadr
CXADR Ig-like cell adhesion molecule.
    
  0.809
LOC100705041
Protein kinase domain-containing protein.
     
  0.808
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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