Gins2 protein (Oreochromis niloticus) - STRING interaction network

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Gins2

DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (212 aa)

Predicted Functional Partners:

gins3

0.999

gins1

0.999

gins4

0.999

cdc45

0.998

mcm5

0.997

mcm4

0.997

mcm2

0.997

mcm3

0.996

mcm6

0.995

MCM7

0.995

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gins2	MCM7	ENSONIP00000007067	ENSONIP00000055028	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.995
Gins2	cdc45	ENSONIP00000007067	ENSONIP00000043787	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	CDC45 cell division cycle 45 homolog (S. cerevisiae).	0.998
Gins2	gins1	ENSONIP00000007067	ENSONIP00000033939	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	GINS complex subunit 1 (Psf1 homolog).	0.999
Gins2	gins3	ENSONIP00000007067	ENSONIP00000013635	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	GINS complex subunit 3.	0.999
Gins2	gins4	ENSONIP00000007067	ENSONIP00000078188	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	0.999
Gins2	mcm2	ENSONIP00000007067	ENSONIP00000032842	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	DNA helicase; Belongs to the MCM family.	0.997
Gins2	mcm3	ENSONIP00000007067	ENSONIP00000057614	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	DNA helicase; Belongs to the MCM family.	0.996
Gins2	mcm4	ENSONIP00000007067	ENSONIP00000011994	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	DNA helicase; Belongs to the MCM family.	0.997
Gins2	mcm5	ENSONIP00000007067	ENSONIP00000010364	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	DNA helicase; Belongs to the MCM family.	0.997
Gins2	mcm6	ENSONIP00000007067	ENSONIP00000019721	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	DNA helicase; Belongs to the MCM family.	0.995
MCM7	Gins2	ENSONIP00000055028	ENSONIP00000007067	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	0.995
MCM7	cdc45	ENSONIP00000055028	ENSONIP00000043787	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	CDC45 cell division cycle 45 homolog (S. cerevisiae).	0.999
MCM7	gins1	ENSONIP00000055028	ENSONIP00000033939	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	GINS complex subunit 1 (Psf1 homolog).	0.994
MCM7	gins3	ENSONIP00000055028	ENSONIP00000013635	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	GINS complex subunit 3.	0.996
MCM7	gins4	ENSONIP00000055028	ENSONIP00000078188	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	0.996
MCM7	mcm2	ENSONIP00000055028	ENSONIP00000032842	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	mcm3	ENSONIP00000055028	ENSONIP00000057614	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	mcm4	ENSONIP00000055028	ENSONIP00000011994	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	mcm5	ENSONIP00000055028	ENSONIP00000010364	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	mcm6	ENSONIP00000055028	ENSONIP00000019721	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999