Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mthfsdMethenyltetrahydrofolate synthetase domain containing. (480 aa)    
Predicted Functional Partners:
nop56
NOP56 ribonucleoprotein homolog.
   
    0.921
Snu13
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
   
    0.919
utp15
UTP15 small subunit processome component.
   
    0.918
Smim12
Small integral membrane protein 12 isoform X3.
   
    0.918
gart
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
   
 0.905
mthfs
5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
     
 0.902
def8
Differentially expressed in FDCP 8 homolog.
      
 0.824
pdcd5
Programmed cell death 5.
      
 0.772
rpp38
Ribonuclease P/MRP 38 subunit.
   
    0.769
mthfd1l
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.
   
 0.758
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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