Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
traddTnfrsf1a-associated via death domain. (291 aa)    
Predicted Functional Partners:
I3K566_ORENI
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.999
Fadd
Uncharacterized protein.
   
 0.999
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.997
LOC100534578
Tumor necrosis factor b (TNF superfamily, member 2).
    
 0.994
LOC100702139
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.993
traf2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.992
LOC109194206
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.992
I3KF49_ORENI
Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.986
LOC100705328
Baculoviral IAP repeat containing 2.
   
 0.983
I3JW29_ORENI
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.981
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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