Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccdc58Coiled-coil domain containing 58. (201 aa)    
Predicted Functional Partners:
Smim12
Small integral membrane protein 12 isoform X3.
    
   0.965
Zzef1
Zinc finger, ZZ-type with EF hand domain 1.
      
 0.870
atp5pf
ATP synthase-coupling factor 6, mitochondrial.
   
  
 0.801
SART1
Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.
    
   0.762
timm21
Translocase of inner mitochondrial membrane 21.
      
 0.755
vbp1
Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.
   
    0.748
ssbp1
Single-stranded DNA binding protein 1.
   
    0.740
ilvbl
IlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family.
      
 0.706
ccdc51
Coiled-coil domain containing 51.
      
 0.704
sf3b6
Splicing factor 3b, subunit 6.
      
 0.696
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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