Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fshbFSH beta subunit. (113 aa)    
Predicted Functional Partners:
cga
Glycoprotein hormones alpha chain precursor.
   
 
 0.963
LOC100534562
Thyrotropin subunit beta.
   
 
 0.961
TSHB
Thyroid stimulating hormone subunit beta.
   
 
 0.961
gnrh3
Gonadotropin-releasing hormone.
      
 0.955
LOC100705740
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
   
 0.930
LOC100691272
5-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.918
LOC100693550
Melanocortin 2 receptor.
   
 
 0.913
I3JS72_ORENI
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
     
  0.909
GPR119
G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family.
     
  0.909
LOC100703512
Prostaglandin E receptor 2a (subtype EP2); Belongs to the G-protein coupled receptor 1 family.
     
  0.909
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.