Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nck1Cytoplasmic protein. (392 aa)    
Predicted Functional Partners:
PAK2
Non-specific serine/threonine protein kinase.
    
 0.952
pak2
Non-specific serine/threonine protein kinase.
    
 0.952
LOC100708294
Non-specific serine/threonine protein kinase.
    
 0.929
pak6
Non-specific serine/threonine protein kinase.
    
 0.928
LOC100696183
Non-specific serine/threonine protein kinase.
    
 0.928
pak5
Non-specific serine/threonine protein kinase.
    
 0.928
wipf1
WAS/WASL interacting protein family, member 1a.
    
 0.926
pak1
Non-specific serine/threonine protein kinase.
    
 0.917
PAK3
P21 (RAC1) activated kinase 3.
    
 0.917
BRK1
Chromosome 3 open reading frame 10.
    
 0.904
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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