Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100692042Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)    
Predicted Functional Partners:
I3JNS9_ORENI
Tight junction protein 1b; Belongs to the MAGUK family.
   
 0.670
LOC100698737
Tight junction protein 1a; Belongs to the MAGUK family.
   
 0.670
LOC100696688
Tight junction protein ZO-3 isoform X1.
   
 0.608
LOC100709536
Occludin a.
   
 0.606
I3KXC4_ORENI
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
 
  0.539
ENSONIP00000031256
Zgc:136892.
   
 
  0.539
ENSONIP00000075843
Claudin-4.
   
 
  0.539
LOC100698417
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  0.520
I3KXU4_ORENI
Claudin 23a.
   
 
 0.509
LOC100703394
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  0.506
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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