Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHLPP2PH domain and leucine rich repeat protein phosphatase 2. (1440 aa)    
Predicted Functional Partners:
sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
    
 
 0.853
usp1
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.798
wdr48
WD repeat domain 48b.
   
 
 0.786
ENSONIP00000000047
RAC-gamma serine/threonine-protein kinase.
    
 0.727
LOC100707971
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.727
LOC100702193
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.727
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.727
LOC100691860
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.727
uchl1
Ubiquitin carboxyl-terminal hydrolase.
    
 0.699
cap1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.692
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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