Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100708589Charged multivesicular body protein 4C. (218 aa)    
Predicted Functional Partners:
chmp7
Charged multivesicular body protein 7.
    
 0.989
pdcd6ip
Programmed cell death 6 interacting protein.
   
 0.987
chmp2a
Charged multivesicular body protein 2A.
   
 0.977
chmp3
Charged multivesicular body protein 3.
   
 0.975
chmp2b
Charged multivesicular body protein 2Bb.
   
 0.969
snf8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
    
 0.958
vps25
Vacuolar protein-sorting-associated protein 25.
    
 0.958
vps36
Vacuolar protein sorting 36 homolog.
    
 0.945
LOC100701199
Charged multivesicular body protein 6a.
   
 0.944
LOC100705156
Charged multivesicular body protein 6.
   
0.944
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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