Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSONIP00000007597Murine retrovirus integration site 1 homolog. (375 aa)    
Predicted Functional Partners:
Itpr3
Inositol 1,4,5-trisphosphate receptor, type 3.
    
 0.928
I3KBJ3_ORENI
Inositol 1,4,5-trisphosphate receptor, type 2.
    
 0.928
LOC100694992
cGMP-dependent protein kinase.
   
 0.917
LOC100707466
cGMP-dependent protein kinase.
   
 0.917
LOC100692694
Inositol 1,4,5-trisphosphate receptor, type 1b.
    
 0.885
I3KSK9_ORENI
Inositol 1,4,5-trisphosphate receptor, type 1a.
    
 0.885
efhb
Uncharacterized protein.
    
 
 0.696
LOC100708987
cGMP-dependent protein kinase.
   
 0.684
prkg2
cGMP-dependent protein kinase.
   
 0.684
I3IVA2_ORENI
Stabilin 1.
   
 
 0.677
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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