Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
shox2Short stature homeobox 2. (301 aa)    
Predicted Functional Partners:
LOC100702161
T-box transcription factor 18.
   
 0.766
HCN4
Hyperpolarization activated cyclic nucleotide gated potassium channel 4.
      
 0.678
hcn4
Hyperpolarization activated cyclic nucleotide-gated potassium channel 4.
      
 0.678
LOC100698703
T-box transcription factor 5a.
    
 0.640
LOC100694461
T-box transcription factor 3b.
    
 0.637
tbx3
T-box transcription factor 3a.
    
 0.637
sox5
SRY-box transcription factor 5.
    
 
 0.635
banp
BTG3 associated nuclear protein.
      
 0.576
ENSONIP00000002644
Si:ch211-263k4.2.
   
 0.534
Prdm16
LOW QUALITY PROTEIN: PR domain zinc finger protein 16.
   
 0.534
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]