Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
otulinUncharacterized protein. (729 aa)    
Predicted Functional Partners:
sharpin
RanBP2-type domain-containing protein.
    
 0.998
ENSONIP00000047919
Ubiquitin B.
    
 0.979
rbck1
RanBP-type and C3HC4-type zinc finger containing 1.
    
 0.971
LOC100708611
Sharpin and rbck1 related.
    
 0.971
LOC100534578
Tumor necrosis factor b (TNF superfamily, member 2).
    
 
 0.955
ENSONIP00000008001
E3 ubiquitin-protein ligase RNF31 isoform X1.
    
 0.928
LOC100707250
Uncharacterized protein.
    
 0.928
ENSONIP00000060526
Si:dkey-181m9.8.
    
 0.928
rps27a
Ribosomal protein S27a.
    
 0.922
SNX27
Sorting nexin 27.
    
 
 0.920
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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