Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
drd2Dopamine receptor D2a; Belongs to the G-protein coupled receptor 1 family. (468 aa)    
Predicted Functional Partners:
gnb4
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
  0.962
LOC100692028
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
  0.962
LOC100703527
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
    
 0.950
I3J8H8_ORENI
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
    
 0.950
LOC100695013
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.
    
 0.950
LOC100702054
Guanine nucleotide binding protein (G protein), beta 5b.
    
 0.944
LOC100703896
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
    
  0.940
gnb1
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
    
  0.940
GNG4
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.
    
 0.938
gng2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.938
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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