STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (4124 aa)    
Predicted Functional Partners:
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.923
rbbp5
Retinoblastoma binding protein 5.
    
 0.908
wdr5
WD repeat domain 5.
   
 0.796
men1
Multiple endocrine neoplasia I.
    
 
 0.792
LOC100698988
E1A binding protein p300 a.
   
 0.776
LOC100700725
E1A binding protein p300 b.
   
 0.776
LOC100709989
CREB binding protein a.
   
 0.761
Crebbp
CREB binding protein b.
   
 0.761
ppie
Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
    
 
 0.751
wsb1
WD repeat and SOCS box containing 1.
   
 0.706
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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