Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (4124 aa)    
Predicted Functional Partners:
rbbp5
Retinoblastoma binding protein 5.
    
 0.968
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.964
wdr5
WD repeat domain 5.
   
 0.963
men1
Multiple endocrine neoplasia I.
    
 0.961
camkmt
Calmodulin-lysine N-methyltransferase.
     
 0.926
LOC100698988
E1A binding protein p300 a.
   
 0.839
LOC100700725
E1A binding protein p300 b.
   
 0.839
LOC100709989
CREB binding protein a.
   
 0.837
Crebbp
CREB binding protein b.
   
 0.837
ENSONIP00000045775
annotation not available
    
 0.834
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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