Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cgnCingulin a. (1202 aa)    
Predicted Functional Partners:
I3JNS9_ORENI
Tight junction protein 1b; Belongs to the MAGUK family.
   
 
 0.938
LOC100698737
Tight junction protein 1a; Belongs to the MAGUK family.
   
 
 0.938
gata4
GATA binding protein 4.
     
  0.916
LOC100696457
Rho/rac guanine nucleotide exchange factor (GEF) 18a.
     
  0.916
arhgef18
Rho/rac guanine nucleotide exchange factor (GEF) 18b.
     
  0.916
LOC100710602
Cingulin b.
     
  0.915
ARHGEF2
Rho/rac guanine nucleotide exchange factor (GEF) 2.
     
 0.877
LOC100704015
Rho guanine nucleotide exchange factor (GEF) 1a.
     
 0.877
I3JD82_ORENI
F11 receptor, tandem duplicate 1.
     
 0.739
I3K4S8_ORENI
Tight junction protein 2a (zona occludens 2); Belongs to the MAGUK family.
   
 
 0.676
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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