Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMX3Thioredoxin related transmembrane protein 3. (451 aa)    
Predicted Functional Partners:
RIC3
Protein RIC-3.
    
 0.879
tmx1
Thioredoxin-related transmembrane protein 1.
   
 
 0.825
unc50
Unc-50 homolog (C. elegans).
      
 0.751
SCCPDH
Saccharopine dehydrogenase a, tandem duplicate 1.
      
 0.709
suox
Sulfite oxidase.
   
 0.691
akr7a2
Aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase).
    
 
 0.649
get1
Guided entry of tail-anchored proteins factor 1.
      
 0.645
Sgpp1
acidPPc domain-containing protein.
    
 
 0.628
SLC35F5
Solute carrier family 35 member F5.
      
 0.620
emc6
ER membrane protein complex subunit 6.
      
 0.618
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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