Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
I3JGN5_ORENIInsulin-like growth factor binding protein 1a. (268 aa)    
Predicted Functional Partners:
LOC100695964
Matrix metallopeptidase 14b (membrane-inserted).
    
 0.819
LOC100709686
Myristoylated alanine-rich protein kinase C substrate b.
      
 0.804
I3KAU3_ORENI
Insulin-like growth factor 2b.
   
 0.752
I3KMU3_ORENI
Insulin-like growth factor 1.
   
 0.667
mmp15
Matrix metallopeptidase 15b.
    
 0.665
anapc16
Anaphase promoting complex subunit 16.
      
 0.652
igfals
Shisa family member 9b.
    
 0.618
hif1an
Hypoxia inducible factor 1 alpha subunit inhibitor.
      
 0.607
igfbp7
Insulin-like growth factor binding protein 7.
     
 0.508
LOC100704156
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.503
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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