STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3JGN5_ORENIInsulin-like growth factor binding protein 1a. (268 aa)    
Predicted Functional Partners:
I3KMU3_ORENI
Insulin-like growth factor 1.
   
 0.764
LOC100695964
Matrix metallopeptidase 14b (membrane-inserted).
    
 0.696
LOC100709686
Myristoylated alanine-rich protein kinase C substrate b.
      
 0.662
I3KAU3_ORENI
Insulin-like growth factor 2b.
   
 0.660
mmp15
Matrix metallopeptidase 15b.
    
 0.515
igfals
Shisa family member 9b.
   
 0.483
LOC100704156
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.473
I3IVU1_ORENI
Uncharacterized protein.
      
 0.421
LOC100696410
Uncharacterized protein.
      
 0.421
I3KYZ4_ORENI
LRRCT domain-containing protein.
   
 0.415
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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