Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
Rprd2Regulation of nuclear pre-mRNA domain-containing protein 2. (946 aa)    
Predicted Functional Partners:
polr2g
Polymerase (RNA) II (DNA directed) polypeptide G-like.
    
  0.957
rpap2
RNA polymerase II associated protein 2.
   
 0.901
supt5h
Transcription elongation factor SPT5.
   
 0.882
rprd1b
Regulation of nuclear pre-mRNA domain containing 1B.
    
 0.876
rprd1a
Regulation of nuclear pre-mRNA domain containing 1A.
    
 0.876
polr2m
RNA polymerase II subunit M.
    
 
 0.856
polr2b
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.833
polr2j
Polymerase (RNA) II (DNA directed) polypeptide J.
    
  0.806
fbf1
Uncharacterized protein.
    
 0.806
Pcf11
PCF11 cleavage and polyadenylation factor subunit.
   
 0.789
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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