Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100702425Teleost multiple tissue opsin b; Belongs to the G-protein coupled receptor 1 family. (413 aa)    
Predicted Functional Partners:
prkci
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.569
LOC100706290
NAD kinase b.
      
 0.564
otos
Otospiralin.
      
 0.564
I3KQQ1_ORENI
SKI-like proto-oncogene a.
    
 
 0.561
samd7
Sterile alpha motif domain containing 7.
      
 0.560
ENSONIP00000008166
Tyrosine kinase, non-receptor, 2a.
      
 0.556
LOC100698860
Actinodin2.
      
 0.556
sec62
SEC62 homolog, preprotein translocation factor.
      
 0.556
LOC100711075
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.502
LOC100696641
Retinal G protein coupled receptor a; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
   
 
0.483
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]