Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSONIP00000008166Tyrosine kinase, non-receptor, 2a. (758 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.924
cdc42
Cell division cycle 42.
    
 
 0.834
nck1
Cytoplasmic protein.
    
 
 0.702
nck2
Cytoplasmic protein.
    
 
 0.702
I3KQQ1_ORENI
SKI-like proto-oncogene a.
      
 0.602
LOC100710037
Growth factor receptor-bound protein 2-B isoform X1.
    
 0.598
LOC100690405
GRB2 related adaptor protein a.
    
 0.598
LOC100710443
GRB2 related adaptor protein 2b.
    
 0.598
ENSONIP00000032932
annotation not available
    
 0.598
LOC100696217
GRB2 related adaptor protein b.
    
 0.598
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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