Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC100702695Transferrin receptor 1b. (768 aa)    
Predicted Functional Partners:
LOC100691316
Serotransferrin-like.
  
 0.952
tfr2
Transferrin receptor 2.
     
  0.916
LOC100695592
Transferrin receptor protein 1.
     
  0.916
LOC100706201
Erythropoietin receptor.
    
 0.897
meltf
Serotransferrin; Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.
  
 0.717
I3J919_ORENI
Serotransferrin; Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.
  
 0.707
mpl
MPL proto-oncogene, thrombopoietin receptor.
     
 0.692
lepr
Uncharacterized protein.
     
 0.675
slc40a1
Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
      
 0.669
ireb2
Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.
   
 
 0.668
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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