Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mad2l2Mitotic arrest deficient 2 like 2. (222 aa)    
Predicted Functional Partners:
rev3l
REV3 like, DNA directed polymerase zeta catalytic subunit.
    
 0.999
rev1
REV1 DNA directed polymerase.
   
 0.998
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
    
 0.985
I3KQQ3_ORENI
Fizzy/cell division cycle 20 related 1b.
   
 0.980
pold2
Polymerase (DNA directed), delta 2, regulatory subunit.
    
 0.974
cdc27
Cell division cycle 27.
    
 0.972
pold3
Polymerase (DNA-directed), delta 3, accessory subunit.
    
 0.972
FZR1
Fizzy/cell division cycle 20 related 1a.
   
 0.969
LOC100694127
WD_REPEATS_REGION domain-containing protein.
   
 0.969
I3IUX9_ORENI
Polymerase (DNA directed), eta.
   
 0.963
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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