Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
capn7Calpain 7; Belongs to the peptidase C2 family. (824 aa)    
Predicted Functional Partners:
I3J4H0_ORENI
IST1 factor associated with ESCRT-III.
    
 
 0.923
LOC100695842
Calpain small subunit 1.
   
 0.849
LOC100700838
Calpain, small subunit 1 b.
   
 0.849
cast
Calpastatin isoform X5.
   
 0.747
oxnad1
Oxidoreductase NAD-binding domain containing 1.
   
  
 0.683
tmem132e
Transmembrane protein 132E.
      
 0.669
mitd1
MIT, microtubule interacting and transport, domain containing 1.
   
  
 0.633
ADI1
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family.
    
   0.598
Topaz1
Protein TOPAZ1 isoform X3.
      
 0.574
mturn
Maturin, neural progenitor differentiation regulator homolog (Xenopus).
      
 0.568
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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