Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cln5CLN5 intracellular trafficking protein. (330 aa)    
Predicted Functional Partners:
LOC100689844
Battenin.
    
 
 0.951
ppt1
Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile).
      
 0.931
cln8
CLN8 transmembrane ER and ERGIC protein.
      
 0.915
Mfsd8
Major facilitator superfamily domain containing 8.
      
 0.841
tpp1
Tripeptidyl peptidase I.
      
 0.837
LOC100690854
CLN6 transmembrane ER protein a.
  
 
 
 0.802
I3JWS4_ORENI
CLN6 transmembrane ER protein b.
  
 
 
 0.797
LOC100705613
Cathepsin F; Belongs to the peptidase C1 family.
      
 0.704
arsg
Arylsulfatase G.
   
 
 0.671
kctd7
Potassium channel tetramerization domain containing 7.
    
 
 0.662
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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