Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rcc1Regulator of chromosome condensation 1. (425 aa)    
Predicted Functional Partners:
ranbp1
RAN binding protein 1.
   
 0.994
LOC100692890
RAN binding protein 2.
   
 0.988
ranbp3
RAN binding protein 3b.
    
 
 0.987
kpnb1
Karyopherin (importin) beta 1.
    
 
 0.978
LOC100700062
Ran GTPase activating protein 1b.
   
 0.972
rangap1
RAN GTPase activating protein 1a.
   
 0.972
ran
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 0.961
adgrd1
Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.
   
 0.961
ENSONIP00000024680
Nucleolar and spindle associated protein 1.
   
 
 0.941
ENSONIP00000061996
annotation not available
    
 0.918
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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