Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wdtc1WD and tetratricopeptide repeats 1. (675 aa)    
Predicted Functional Partners:
ddb1
Damage-specific DNA binding protein 1.
    
 0.991
Cul4b
Cullin-4B.
    
 0.942
cul4a
Cullin 4A; Belongs to the cullin family.
    
 0.942
dcaf10
WD repeat domain 32.
   
 
 0.909
dcaf4
WD repeat domain 21.
     
 0.899
cops8
COP9 signalosome subunit 8.
    
 0.887
dcaf5
Ddb1 and cul4 associated factor 5.
     
0.869
ercc8
Excision repair cross-complementation group 8.
     
 0.864
Dda1
DET1- and DDB1-associated protein 1.
    
 0.863
DDA1
DET1 and DDB1 associated 1.
    
 0.863
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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