Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
esf1ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae). (757 aa)    
Predicted Functional Partners:
Ddx10
RNA helicase.
   
 
 0.992
nol10
Nucleolar protein 10.
   
 
 0.990
utp6
UTP6 small subunit processome component.
   
 
 0.988
utp3
UTP3 small subunit processome component.
   
 
 0.987
nol6
Nucleolar protein 6.
   
 
 0.983
mphosph10
U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family.
   
 
 0.983
I3KZE4_ORENI
Apoptosis antagonizing transcription factor.
   
 
 0.982
utp18
WD_REPEATS_REGION domain-containing protein.
   
 
 0.981
bysl
Bystin-like.
   
 
 0.976
nat10
RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
   
 
 0.976
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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