STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100694452Sprouty related EVH1 domain containing 2a. (492 aa)    
Predicted Functional Partners:
Nf1
Neurofibromin 1b.
    
 0.893
nek2
NIMA-related kinase 2.
    
 0.641
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.563
hras
HRas proto-oncogene, GTPase a.
   
 0.563
CSDE1
Cold shock domain containing E1, RNA-binding.
   
 0.563
LOC100703836
Zgc:55558.
   
 0.563
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
     
 0.561
ENSONIP00000038419
Profilin-2 isoform X2.
   
 0.496
LOC100700117
Profilin; Belongs to the profilin family.
   
 0.496
pfn2
Profilin; Belongs to the profilin family.
   
 0.496
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.