Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
I3JIC9_ORENIUncharacterized protein. (423 aa)    
Predicted Functional Partners:
mad1l1
Mitotic arrest deficient 1 like 1.
    
 
 0.700
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
    
   0.693
ddx11
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11.
    
 
 0.693
phgdh
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.632
nfatc2
Nuclear factor of activated T cells 2a.
      
 0.621
smc3
Structural maintenance of chromosomes protein.
    
   0.585
LOC100692924
Structural maintenance of chromosomes protein.
    
   0.554
smc1a
Structural maintenance of chromosomes protein.
    
   0.554
ncln
Nicalin.
   
  
 0.552
pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
 0.530
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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